Group Leader
Tony studies the structure and function of an essential class of enzymes, DNA topoisomerases, which break the double-stranded helix of DNA.
Tony’s research aims to reveal mechanisms of action of DNA topoisomerases such as DNA gyrase, to understand how they might be disrupted.
His research then involves the development of novel compounds which target these enzymes, identifying potential new antibiotic, herbicide and anti-plasmodial compounds.