Royal Society Research Fellow
Andy works on natural product biosynthesis in bacteria with a particular interest in ribosomally-synthesised peptides.
Bacteria are capable of converting simple linear peptide chains into complex chemicals in relatively few biosynthetic steps.
Andy’s research involves the use of techniques such as mass spectral networking to discover related groups of molecules and to understand how these are made.
This research explores the biochemical pathways involved and the potential role of these compounds in biology and for exploitation in medicine and agriculture.
- Peptide modification in bacteria to make novel compounds
- Mass spectral networking to identify new compounds
- The role of new compounds for exploitation, e.g. in disease suppression in plants and for the treatment of human disease