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Dr Kevin Tyler

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Biological Chemistry


Infection Biology

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Senior Lecturer

Cellular Microbiology

We are investigating the way in which Trypanosoma cruzi is able to manipulate host cardiomyoctes to facilitate invasion and for intercellular survival. Our approach is primarily by real-time fluorescence microscopy of host/fluorescent protein chimaeras and fluorescent probes and by use of molecular and chemical intervention.

Trypanosome Cell Biology

We are investigating the requirements and mechanism of cytological change in trypanosomes; in particular, the roles of cytoskeleton and membrane rafts.

Parasite Virulence

We are investigating the evolution of parasite molecules which are associated with host specificity and virulence in a number of parasites.

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