Research Group Leader
Barrie researches the discovery and biosynthesis of microbial natural products.
He is particularly interested in identifying new compounds with antibiotic and antifungal properties, and in characterising the biosynthetic pathways and biochemical mechanisms by which they are made.
Barrie’s research involves investigating the targets for these compounds and elucidating their mode of action.
This research generates new therapeutic compounds whilst providing a deeper understanding of the evolution of molecular diversity.
- Identification of microbial natural products and targets
- Understanding the mode of action of therapeutic compounds
- Characterising biosynthetic pathways